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Cornea transplant (corneal grafting) is the process by which a diseased cornea of the patient is replaced by the donated cornea graft or tissue. The surgery can be done in total with penetrating keratoplasty and also in part with lamellar keratoplasty. In this procedure, a clear healthy corneal is placed by removing the diseased opaque cornea in order to restore the lost sight by permitting the light rays to enter with the help of the clear transplanted cornea.
An external clear covering of the eye which contains the colored pupil and the iris is termed as Cornea. If there is any damage to the cornea, then it can become swollen and can affect the smoothness and its clarity. Cornea is a very powerful refracting surface which is around 2/3rd part of the eye. It is very essential part of the eye and is required for clear vision. It becomes a clear window to look through and its clarity is necessary for good vision. Diseases of the cornea will lead to loss of transparency, reducing the vision. The impaired functioning of the cornea can cause injury, genetic diseases, infections and malnutrition. The first line treatment comes in the form of medicine and the cornea transplant become a necessity for people losing almost 70 per cent of the vision in one or both the eyes.Converting the food to energy Regulation of the blood clot Forming the bile and then production of proteins used for blood plasma Clear of the blood from poisonous substances like drugs
* Penetrating (full thickness) Cornea Transplant : This kind of transplant involves transplanting all the layers of the cornea from the donor. * Lamellar Cornea Transplant : In this the surgeon only replaces some of the layers of the cornea with the transplant.
Lamellar transplants are the most appropriate transplant when the disease process is limited to only a portion of the cornea.Biliary Atresia – This condition occurs from either absence of the bile ducts or abnormal development of the same. Acute Hepatic Necrosis – This condition is caused because the tissue in the liver dies. Liver Cancers – Primary tumors in the liver, and not yet spread to the external parts of the liver. Metabolic Disease – This is a condition, caused from the chemical activity, caused by the liver in the cells. Autoimmune Hepatitis – Damage and destruction of the liver because of the chronic inflammation caused in the liver.
* Vision cannot be corrected with eyeglasses or contact lenses *In the case of swelling which cannot be healed by any medications. * Hereditary corneal failure, such as Fuchs’ Dystrophy * A steep curving (Keratoconus) of the cornea * Corneal failure after other eye surgery, such as cataract surgery * Injury leading to scarringBlood vessels blocked in the newly transplanted liver Infection Block of bile duct Bile Leakage No function of the new liver. Treatment regimen noncompliance Serious liver disease persisting, even after the transplantation Other medical conditions, like sever cardiac problem, which could not tolerate the hard surgical procedure Difficult treatment of current or recurring infection Alcohol consumption Metastatic cancer, spread around the source location
The surgical process of cornea transplant does not require any hospitalization and is performed under general anesthesia. The tissue is examined thoroughly before donor corneas are used for transplant. To control the continuous blinking and eye movement, an injection is released into the eyes of the patient. Many times a surgeon also uses eye drops to numb the eye.
The surgeon then examines the concerned area to understand the requirement of the size of the donor tissue. The surgeon first removes a similar shaped button part of the tissue from the patient’s affected cornea and then places a similar shaped button from the donor tissue. This button is then sutured into a proper place. At the end, the surgeon will cover the patient’s eye with a plastic shield to protect it from being rubbed.Urgency – based on the critical condition of the patient Diagnostic Tests – to assess the liver and overall status of health of the patient. Psychological and social evaluation – it includes assessing the stress, family support, financial condition, etc., which influence the final outcome of the transplantation. Blood Tests – to assess matching potential of the donor liver with the liver of the patient
*The total recovery time for a corneal transplant can be up to a year or longer * For the first several weeks, heavy exercises and lifting are prohibited * Stitches usually are removed after 3 to 17 months, depending on the health of the patient’s eye and the rate of healingYou have to wear a gown after removing your cloths It starts with IV or intravenous line on the hand. Heart and blood pressure monitoring catheter are inserted to the wrist and neck. Additional catheters may be inserted at subclavian areas. You need to lye on the table. Excessive hair is removed at the site of surgery A catheter is arranged to drain urine After sedation, a tube is inserted into the lungs to control breathing through a ventilator. Skin is cleaned using an antiseptic solution A slant incision is done under the ribs. The diseased liver is separated from the structure and surrounding organs to remove and the veins and arteries are clamped to control the flow of blood to the liver Donor liver is taken and connected to the blood vessels of the patient, and blood flow is established. Bile ducts are connected Incision is closed Drain may be needed to place in the site of incision to control swelling Dressing is done
* Be careful not to rub or press your eye * Try to avoid rubbing your eyes * Try to avoid excessive and hard exercises * Use the eye drops as prescribed * Wear eye glasses for protection * Before starting driving first confirm with your doctor * Call doctor if you have any questions about home-care instructions
* It reduces the pain that is caused by disease or trauma * A cornea transplant restores a person’s vision
Corneal transplant is regarded as the highly successful organ transplant surgery. The rate of success depends greatly on the extent and nature of injury to the eye. The rate is as high as 89% with Keratoconus, 73% with Fuchs’ Dystrophy and 60-70 % with corneal scarring.
India is one of the regularly visited medical tourism destinations. India is known for its healthcare infrastructure with the latest technology and facilities. Due to this reason, the cost of corneal transplants in India is very affordable as compare to other countries.
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